Integrate Math With Traditional Visual Analysis
BCS Solves The IHC Testing Problem By Delivering Calibration And SPC As Recommended By IHC Community Leadership
Calibration
for inter-laboratory accuracy
Statistical Process Control
for intra-laboratory accuracy
Boston Cell Standards Quality Platform For IHC
BCS Quality platform delivers Calibration and SPC to IHC for the first time
Integration of Calibrators, Quantitative Controls, Image Quantification Software, and Imaging
Consumable
IHCalibrators®
- Enable calculation of LOD and assay dynamic range
- Align labs to one another
- Align instruments within a lab to one another
- Align clinical trial sites with one another
- Verify lot-to-lot reagent comparability
- Optimize antibody dilution for maximal sensitivity and minimal background
- Troubleshoot IHC assay problems
Consumable
IHControls®
- Quantitative Controls Enable SPC
- Create Levey-Jennings graphs
- Establish control ranges for acceptable performance
- Compare control values to peers
- SPC aligns a lab to itself over time
- Verify heater consistency at each instrument slide position
- Consistent biomarker concentrations from lot to lot
- Simple and efficient management of IHC control inventory
- Ready supply of hard-to-find IHC controls
METRIC Software System
SPC Daily Report
- Analyze IHControls® and provide daily Levey-Jennings graph (SPC)
- Establish quantitative control ranges
IHC Calibration Report
- Analyze IHCalibrators® and calculate LOD and assay dynamic range
- Compare your LOD with peer labs or published data
BCS Quality Platform For IHC
When And How Do I Use IHCalibrators® Versus IHControls®?
Integration of Calibrators, Quantitative Controls, Image Quantification Software, and Imaging
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IHCalibrators®
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IHControls®
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Why Use?
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Align your lab with other IHC labs. Compare your lab with peer labs |
Align your lab with itself over time |
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Form Factor
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15 small spots on a slide |
Suspension stored in a vial; apply one control drop to each tissue slide |
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Material
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Glass microbeads covalently coated with a fluorescent-labeled biomarker |
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Measurement traceability to a NIST reference standard
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Yes |
Yes |
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METRIC calculations
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Dynamic range and Lower Limit of Detection (LOD) |
Statistical Process Control (Levey-Jennings graph) |
Decades of Major technical innovations
BCS has developed many new technologies over decades to bring Calibration and SPC to IHC
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Calibration and SPC introduce terminology
that is new to IHC
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Learn how BCS had to innovate each new technology to deliver Calibration and SPC to IHC
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Analytic Sensitivity
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Calibrator
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Control Range
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Dynamic Range
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Levey-Jennings Graph
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Lower limit of detection (LOD)
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Quantitative Control
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Reference Standard
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Traceable unit of measure
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