PRESS RELEASE: Calibration Transforms Accuracy in HER2-Low Breast Cancer Testing Read Now »

IHControls®

Multiplexed. IHControls® are grouped together so that a single control will be useful for multiple different primary antibodies, often to different protein biomarkers. The groups are usually organized by analyte or subject area. For example, HER2, ER, and PR are grouped together as a breast cancer panel.

Matched. In addition to the different analyte specificities, there are also multiple different concentrations of each that are often available. This ensures that your lab uses a concentration matched to your stain. Our studies have demonstrated that controls with too high a concentration are insensitive. There is an approximately ten-fold difference in antigen concentration between each level. We recommend using the lowest antigen concentration that provides an easily detectable stain. That concentration may not be the same for HER-2, ER and PR and should be determined in your lab.
IHControls’ Safety Data Sheet

How to use IHControls®
Marker Description Level Intended Target Antibodies Product Code Regulatory Status
Breast Cancer Panel ER/PR/HER2 multi-controls High HER2 CB11, HER2 4B5, HER2 DG44, ER EP1, PR 636, PR 16, ER EP1 BRLS11 IVD/RUO*
ER/PR/HER2 multi controls Medium HER2 CB11, HER2 4B5, HER2 DG44, PR 636, PR16, ER EP1, ER 6F11, PR 1294, PR 1E2, ER SP1 BRL2U04 IVD/RUO*
ER/PR/HER2 multi controls Low HER2 CB11, HER2 4B5, HER2 DG44, PR 636, PR16, ER EP1, ER 6F11, PR 1294, PR 1E2, ER SP1 BRL2W08 IVD/RUO*
PD-L1 PD-L1 controls High SP263, 22C3, 28-8, ZR3, 73-10, E1L3N, SP142 PDLH RUO
PD-L1 controls Medium SP263, 22C3, 28-8, ZR3, 73-10, E1L3N, SP142 PDLM RUO
PD-L1 controls Low SP263, 22C3, 28-8, ZR3, 73-10, E1L3N, SP142 PDLL RUO

*In Vitro Diagnostic (IVD) for US Market only – Reference FDA 510(k) Number K220163. Research Use Only (RUO) for non-US markets. HER2 DG44 antibody not intended for use under IVD.

Contact Us to Order IHControls®